Brand: New England Biolabs (NEB) · SKU: M0437 · MPN: M0437 · Category: Components

NEB M0437 T4 RNA Ligase 1 High Concentration is a 30,000 U/ml enzyme for ligating single-stranded RNA and DNA substrates.
| Product Number | M0437 |
|---|---|
| Reaction Buffer | 1X T4 RNA Ligase Reaction Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM DTT, pH 7.5 @ 25°C) |
| Unit Definition | The amount of enzyme required to convert 1 nanomole of 5´-[32P]rA16 into a phosphatase-resistant form in 30 minutes at 37°C |
| Heat Inactivation | 65°C for 15 minutes |
| Required Supplement | 1 mM ATP |
| Storage Temperature | -20°C |
| Enzyme Concentration | 30,000 units/ml (High Concentration) |
| Recommended Incubation | 25°C |
| Warranty | 3-Year Warranty |
| Weight | Not specified |
| Dimensions | Not specified |
NEB M0437 T4 RNA Ligase 1 (ssRNA Ligase), High Concentration is a molecular biology enzyme designed for ligation of single-stranded RNA and DNA. It catalyzes formation of a 3′ to 5′ phosphodiester bond between a 5′ phosphoryl-terminated donor and a 3′ hydroxyl-terminated acceptor, using ATP. The high-concentration formulation provides 30,000 units/ml, three times the concentration of NEB's standard T4 RNA Ligase 1, making it useful for lower-volume reactions. M0437 is supplied with T4 RNA Ligase Reaction Buffer, PEG 8000, and ATP. It is suitable for applications including RNA cloning and RNA/DNA ligation.
Yes, this NEB T4 RNA Ligase 1 High Concentration M0437 ssRNA Ligase (M0437) is 100% genuine New England Biolabs (NEB) hardware. All our products are verified by certified technicians and come with clean serial numbers ready for service contract registration.
This NEB T4 RNA Ligase 1 High Concentration M0437 ssRNA Ligase includes our standard 3-Year Warranty covering all manufacturing defects. We also offer advanced replacement options for minimal downtime.
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Yes, we have a 30-day return policy on all products. Restocking fees may apply for opened items. Please see our return policy for complete details.
Please check the specifications tab for detailed compatibility information. Our technical team is available to assist with compatibility questions for the M0437.