Brand: Various (e.g., Hello Bio, Chemodex, Enzo Life Sciences, ZETA LIFE) · SKU: JC10 · MPN: Varies by supplier (e.g., T0103, ENZ-52305) · Category: Components
JC-10 is a highly soluble, membrane-permeant, dual-emission fluorescent probe used to assess mitochondrial membrane potential (MMP) in cells, tissues, or purified mitochondria. In healthy cells with polarized mitochondria, JC-10 aggregates, emitting strong orange fluorescence (Ex/Em: 540nm/590nm). In cells with depolarized mitochondria (a sign of apoptosis or stress), it reverts to its monomeric form, resulting in a shift to green fluorescence (Ex/Em: 490nm/525nm). It is considered a superior, more water-soluble analog to the JC-1 dye. Applications include fluorescence microscopy, flow cytometry, and high-throughput screening. It can also be used as a sensitive indicator for early apoptosis.
| Storage | Store at -20°C, protect from light |
|---|---|
| Solubility | Highly soluble in aqueous buffers (superior to JC-1) |
| Application | Assess Mitochondrial Membrane Potential (MMP) |
| Excitation/Emission (Monomer) | Ex: 490nm / Em: 525nm (or Ex: 515nm / Em: 529nm) |
| Fluorescence Shift (Polarized) | Orange (J-aggregate) |
| Excitation/Emission (Aggregate) | Ex: 540nm / Em: 590nm (or Ex: 525nm / Em: 590nm) |
| Fluorescence Shift (Depolarized) | Green (Monomer) |
| Warranty | Not applicable (Laboratory chemical/reagent) |
| Weight | Not specified (typically sold in small quantities/kits) |
| Dimensions | Not specified (typically sold in small quantities/kits) |
The JC-10 fluorescent dye is a ratiometric probe used to measure mitochondrial health and detect early apoptosis by monitoring changes in the mitochondrial membrane potential. Its high aqueous solubility makes it convenient for various biological assays.
Yes, this JC-10 Mitochondrial Membrane Potential Probe (JC10) is 100% genuine Various (e.g., Hello Bio, Chemodex, Enzo Life Sciences, ZETA LIFE) hardware. All our products are verified by certified technicians and come with clean serial numbers ready for service contract registration.
This JC-10 Mitochondrial Membrane Potential Probe includes our standard 3-Year Warranty covering all manufacturing defects. We also offer advanced replacement options for minimal downtime.
We offer free ground shipping which typically takes 3-5 business days. Expedited shipping options are available at checkout for faster delivery.
Yes, we have a 30-day return policy on all products. Restocking fees may apply for opened items. Please see our return policy for complete details.
Please check the specifications tab for detailed compatibility information. Our technical team is available to assist with compatibility questions for the JC10.